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Synthetic Gene DataBase
 

Browse Natural Genes


 
  All 243 natural genes in SGDB.
No. Wild-Type Gene Name Protein Function Source Species Length(bp)
1 (1,3-1,4)-beta-glucanase Hydrolyzes glycosidic linkages in cell walls of endosperm. Hordeum vulgare 1005
2 2,5-DKGR A,B Catalyzes 2,5-diketo-D-gluconic acid to 2-keto-L-gluconic acid Corynebacterium sp. 837
3 A-dmDT390-bisFv(G4S) Immunotoxin which intoxicates T cells and halts protein synthesis. Corynebacterium diphtheriae 0
4 AAT serine protease inhibitor Homo sapiens 1257
5 aceGFP (acoeGFP ) Reporter gene (GFP-like protein) Aequorea coerulescens (belt jellyfish) 717
6 act (activator) Helper protein for lipase; Chaperone Pseudomonas sp. 1035
7 aeqD Produces green fluorescent protein when bound to calcium. Aequorea victoria 591
8 afp antifungal protein which acts against filamentous fungi Aspergillus giganteus 285
9 Ag85B fibronectin-binding Mycobacterium tuberculosis 978
10 aglA Catalyzes the hydrolysis of galactose Cyamopsis tetragonoloba 1236
11 AMA1 Help invasion (apical membrane antigen) Plasmodium falciparum (malaria) 1566
12 AMA1 (3D7) Help invasion (apical membrane antigen) Plasmodium falciparum (malaria) 1869
13 AMA1 (FVO) Help invasion (apical membrane antigen) Plasmodium falciparum (malaria) 1816
14 AMA1-3D7 Blood cell invasion (antigen) Plasmodium falciparum (malaria) 1869
15 AMA1-FVO Help invasion (apical membrane antigen) Plasmodium falciparum (malaria) 1566
16 Angiogenin Angiogenesis Homo sapiens 375
17 apoA-I Structural component of high density lipoprotein, activator of LC acyltransferase, and acceptor of cholesterol Homo sapiens 897
18 Art v 1 precursor major pollen allergen Artemisia vulgaris 399
19 avd Binds biotin, prevents carboxylase reactions Gallus gallus 459
20 BGL2 Involved in cell wall maintenance Saccaromyces cerevisiae 942
21 Blo t 5 Allergen Blomia tropicalis (house dust mite) 405
22 BPV-1 L1 capsid protein bovine papillomavirus type 1 (synthetic) 1488
23 BPV-1 L2 bovine papillomavirus type 1 (synthetic) 1410
24 c-Fos Oncogene, dimerize with c-Jun to bind TRE Mus musculus 1143
25 CCR5 co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Homo sapiens (human) 1059
26 CEA Glycosylated cell surface intracellular adhesion molecule, human tumor marker Homo sapiens 2109
27 cGATA-1 Gallus gallus 915
28 CHGA unknown Homo sapiens 1987
29 chy Bos taurus 1146
30 COE epitope which induces PEDV antibodies Porcine Epidemic diarrhea virus (PEDV) 426
31 Cre Cre recombinase Enterobacteria phage P1 1032
32 cry1Ac crystal protein Bacillus thuringiensis 3537
33 cryIA(b) Insect control in crops Bacillus thuringiensis 1845
34 cryIA(b) Insecticidal for rice pests Bacillus thuringiensis 3468
35 cryIA(c) Insecticidal for rice pests Bacillus thuringiensis 1857
36 CSP281A (circumsporozoite protein aa 281-290) H-2Kd- restricted CTL epitope Plasmodium yoelii 33
37 CTTETANG Is a fragment protein of Tetanus toxin (fragment C) Clostridium tetani 1359
38 CYP73A17 Enzyme: cinnamate-4-hydroxylase (C4H) cytochrome P450 Triticum aestivum 1506
39 CYP85A5 Cytochrome P450 Triticum aestivum 1626
40 Cyt2Aa1 Insecticide and possible development of anti-tumor immunotoxins. Bacillus thuringiensis 780
41 Derp 1 Dermatophagoides pteronyssinus 909
42 DsRed Reporter gene Discosoma sp (coral) 678
43 DsRed (drFP583) Reporter gene (Red fluorescent protein FP583) Discosoma sp (coral) 678
44 E1 Replication protein. human papillomavirus (HPV-16) 1950
45 E1 Replication protein. Canine oral papillomavirus 1794
46 E2 regulatory protein human papillomavirus (HPV-16) 1098
47 E2 Regulation. Canine oral papillomavirus 1158
48 E4 Canine oral papillomavirus 357
49 E5 (HPV-16 E5) membrane protein human papillomavirus (HPV-16) 252
50 E5 (wt16E5) Modulate endosomal pH and signal transduction pathways human papillomavirus type 16 (HPV16) 252
51 E7 Oncogene Human papillomavirus 297
52 E7 Oncogene Human papillomavirus (HPV) 297
53 E7 to eliminate viral oncogenic antigen expression cells such as HPV16-related cancer cells. Human papillomavirus 297
54 E7 transmembrane protein, immunogenic protein. human papillomavirus (HPV-16) 297
55 E7 Transforming. Canine oral papillomavirus 294
56 EBA-175 erythrocyte-binding protein (EBA-175 Region II), binds to its erythrocyte receptor sialic acids on glycophorin A Plasmodium falciparum 1848
57 EBA-175 Sialic acid-binding protein Plasmodium falciparum 3D7 4263
58 EGFP reporter gene Aequorea victoria 798
59 EI Inhibits cysteine and aspartic acid proteases Actinia equina 696
60 eIF2A Catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits in humans Homo sapiens 1704
61 env envelope protein. human Immunodeficiency Virus (HIV-1) 2607
62 env human immunodeficiency virus (HIV1) 2562
63 Env (gp120) envelope glycoprotein human Immunodeficiency Virus (HIV-1) 2544
64 Env (gp160) Envelope potein human immunodeficiency virus (HIV1) 2463
65 env (gp160) envelope protein (receptor binding and fusion) Human immunodeficiency virus 1 (HIV-1) 2565
66 env (JRFL) envelope glycoprotein human immunodeficiency virus (HIV1) 2544
67 epoA type I polyketide synthase Polyangium cellulosum (Sorangium cellulosum) 4266
68 epoB type I polyketide synthase Polyangium cellulosum (Sorangium cellulosum) 4233
69 epoC type I polyketide synthase Polyangium cellulosum (Sorangium cellulosum) 5499
70 epoD type I polyketide synthase Polyangium cellulosum (Sorangium cellulosum) 21744
71 epoE type I polyketide synthase Polyangium cellulosum (Sorangium cellulosum) 11397
72 epoF type I polyketide synthase Polyangium cellulosum (Sorangium cellulosum) 7320
73 erythropoietin (EPO) Erythropoietin mediates an immune response that limits damage to the heart, the nervous system and other tissues following injury. Homo sapiens 582
74 FALVAC-1 NCO Multistage candidate vaccine against Plasmodium falciparum Plasmodium falciparum 972
75 firefly luciferase reporter gene Photinus pyralis 1653
76 Fnta Catalyzed 15-carbon moiety to C-terminal cysteine Rattus norvegicus 264
77 Fnta Catalyzes transfer of farnesyl isoprenoid group from farnesyl diphosphate to the CaaX cysteine of a variety of cellular proteins. Rattus norvegicus 1134
78 fructosyl amine-oxygen oxidoreductase (FAOP) Amadoriase; Enzymatic determination of the quantity of glycated proteins Penicillium janthinellum 1314
79 Fruitfly lachesin mRNA Drosophila melanogaster 2110
80 FSoCut Cutinase is a small esterase which acts to degrade the exterior cutin of plants. Fusarium solani 789
81 GADD34 Human homolog of mouse MyD116 that is expresses in mylekoid leukemia cells induced to differentiate by interleukin Homo Sapiens 2025
82 gag antigen human immunodeficiency virus (HIV1) 1503
83 gag DNA binding ( GO:0003677 ), RNA binding ( GO: 0003723), RNA-directed DNA polymerase activity ( GO: 0003964) human Immunodeficiency Virus (HIV-1) 0
84 gag DNA binding ( GO:0003677 ), RNA binding ( GO: 0003723), RNA-directed DNA polymerase activity ( GO: 0003964) human Immunodeficiency Virus (HIV-1) 1485
85 gag DNA binding ( GO:0003677 ), RNA binding ( GO: 0003723), RNA-directed DNA polymerase activity ( GO: 0003964) human Immunodeficiency Virus (HIV-1) 1503
86 gag gag protein Simian immunodeficiency virus 1533
87 gag DNA binding ( GO:0003677 ), RNA binding ( GO: 0003723), RNA-directed DNA polymerase activity ( GO: 0003964) human Immunodeficiency Virus (HIV-1) 1509
88 gag DNA binding ( GO:0003677 ), RNA binding ( GO: 0003723), RNA-directed DNA polymerase activity ( GO: 0003964) human Immunodeficiency Virus (HIV-1) 1509
89 gag DNA binding ( GO:0003677 ), RNA binding ( GO: 0003723), RNA-directed DNA polymerase activity ( GO: 0003964) human Immunodeficiency Virus (HIV-1) 1509
90 gag Simian immunodeficiency virus 1533
91 gag (Du422 gag) DNA binding ( GO:0003677 ), RNA binding ( GO: 0003723), RNA-directed DNA polymerase activity ( GO: 0003964) human immunodeficiency virus (HIV1) 1479
92 gag-pol Enzyme precursor human immunodeficiency virus (HIV1) 4307
93 gag-pol human Immunodeficiency Virus (HIV-1) 0
94 gag-pol human Immunodeficiency Virus (HIV-1) 0
95 gag-pol DNA recombination, RNA-dependent DNA replication, DNA binding, RNA binding, RNA-directed DNA polymerase activity human Immunodeficiency Virus (HIV-1) 4308
96 gag-pol Enzyme precursor human immunodeficiency virus (HIV1) 4307
97 gag-pol human immunodeficiency virus (HIV1) 4308
98 gag/pol wt structural genes Bovine immunodeficiency virus 4427
99 GCB Breaks down membrane glycosphingolipids in cells. Homo sapiens 1611
100 gfp produces green fluorescence with only a cofactor of oxygen, reporter gene Aequorea victoria 717
101 GFP Reporter gene Aequorea victoria 717
102 GFP (Green Fluorescent Protein) reporter gene Aequorea victoria 714
103 gfp (humanized) reporter gene Aequorea victoria 717
104 GFP (synthetic) reporter gene Aequorea victoria 716
105 GFP-S65T reporter gene Aequorea victoria 795
106 gfp10* reporter gene Aequorea victoria 714
107 GFPmut3 reporter gene Aequeora victoria 726
108 GFPncb Reporter gene Aequorea victoria 717
109 GL6 Allows adhesion to colonicmucin for colonization and target cells. Entamoeba histolytica 3847
110 GLuc (Gaussia luciferase) reporter gene Gaussia princeps 558
111 GP (α-glucan phosphorylase) catalyzes phosphorolysis of α-1,4-glucan Solanum tuberosum 2517
112 gp120 envelope glycoprotein Human immunodeficiency virus 1 (HIV-1) 642
113 gp120R2 (env) envelope glycoprotein human Immunodeficiency Virus (HIV-1) 2562
114 Green fluorescent protein (GFP) Reporter gene Aequorea victoria 717
115 green fluorescent protein (GFP) Reporter gene Aequorea victoria 717
116 green fluorescent protein (GFP) Reporter gene Aequorea victoria 717
117 growth hormone 1 (gh1) Growth hormone Homo sapiens 654
118 GSTM2 glutathione S-transferase Homo sapiens 657
119 H(A12-M)Y13 Hydrolyzes glycosidic linkages in cell walls of endosperm. Bacillus amyloliquefaciens, Bacillus macerans 720
120 Hab18GEF/CD147 Hepatoma associated antigen Homo sapiens (human) 558
121 hCG (human chorionic gonadotropin) Produced by the placenta to stimulate ovaries to produce steroids that maintain pregnancy Homo sapiens 879
122 hG-CSF Stimulates the proliferation, differentiation, and function of neutrophil granulocyte progenitor cells and mature neutrophils. Homo sapiens 525
123 Hgp (HIV gag-pol) structural genes HIV-1 4283
124 hGSTA4 Glutathione transferase Homo sapiens 669
125 hIGF-1 Stimulates proliferation and differentiation of cells Homo sapiens 393
126 hIL-18 IFN-gamma inducing factor Homo sapiens 471
127 hIL-6Ec Multifunctional cytokine, which also is an important component of the inflammatory cascade. Homo sapiens 639
128 HIS1 ATP phosphoribosyltransferase Candida albicans 897
129 HIS3 Anti-microbiral activity against bacteria and fungi in salivatory glands. Homo sapiens 156
130 hRGFP (partially humanized, red shifted GFP) reporter gene Aequorea victoria 717
131 IA-2ic antigen of auto-immune diabetes, no natural enzyme activity Homo sapiens 2940
132 IFN-alpha Known to display antiviral, antiproliferative, and immunomodulatory activities. Homo sapiens 805
133 IFN-alpha-2B Treatment of various disease and diagnostics. Homo sapiens 501
134 IFN-k Activates the interferon-stimulated response signaling pathway Homo sapiens 624
135 IL-2 Mediates immune response by acting as growth factor for T cells Homo sapiens 402
136 Immunoglobulin kappa chain (17-1A) Antibody Mus musculus 732
137 int (integrase) site-specific recombinases, DNA breaking-rejoining enzymes Micromonospora rosaria 1134
138 Integrase Enzyme human immunodeficiency virus (HIV1) 867
139 L1 for preventing viral infection. Human papillomavirus 1596
140 L1 Major capsid protein, influences production of VLPs (virus-like particles) Human papillomavirus (HPV) 1506
141 L1 (BPV1 L1) Capsid protein Bovine papillomavirus type 1 1488
142 L1ori Major structural protein, generates VLP (virus-like particles) Human papillomavirus (HPV) 1518
143 L1ori minor capsid protein human papillomavirus (HPV-16) 1518
144 L1ori major capsid protein human papillomavirus (HPV-16) 1518
145 L2ori human papillomavirus (HPV-16) 1422
146 LacZ reporter gene E. coli 3069
147 lip (lipase) Catalyzes the hydrolysis of triacylglycerols Pseudomonas sp. 1095
148 lip1 Candida rugosa 0
149 lipA (lipase) Catalyzes the hydrolysis of triacylglycerols Burkholderia glumae (Chromobacterium viscosum) 1077
150 lipB (helper protein) Helper protein for lipA; Chaperone Burkholderia glumae (Chromobacterium viscosum) 1062
151 LK-w (lumbrokinase) fibrinolytic enzyme Lumbricus rubellus 849
152 LLO (listeriolysin O bps. 91-99) cytotoxin (sulfhydryl-activated) which permits escape from phagocytic vesicles and entry into the cytosol Listeria monocytogenes 57
153 LLO91A (listeriolysin O aa 91-99) H-2Kd- restricted CTL epitope Listeria monocytogenes 30
154 LMP-3 (LIM mineralization protein-3) involved in bone development Homo sapiens 462
155 lsc Antibody (large single chain) Homo sapiens 1893
156 MSP-1 merozoite surface protein 1 (MSP-1) Plasmodium falciparum 1065
157 mtGrx Glutaredoxin-like protein Methanobacterium thermoautotrophicum 0
158 MTS1 Encodes a protein called p16, which inhibits CDK4/6 in humans. Homo sapiens 351
159 nanH Cleaves sialic acid from glycoprotein, glycolipids, and sugars Clostridium perfringens 1149
160 natSU glycoslyated surface protein of virus Equine infectious anemia virus (EIAV) 1332
161 nBlo t 5 (native) major IgE-binding protein Blomina tropicalis 537
162 nef protein binding human immunodeficiency virus (HIV1) 642
163 nef Protein binding human Immunodeficiency Virus (HIV-1) 621
164 Neurofibromin, Human Type 1 catalyzes RAS inactivation (tumor suppressor gene) Homo sapiens 1005
165 NiV-F cell mediated fusion Nipah Virus 2343
166 NiV-G cell mediated fusion Nipah Virus 1809
167 NR Catalyzes the rate-limiting step in the pathway of inorganic nitrogen assimilation. Spinacia oleracia 375
168 NS1 A non-stractural protein that mediates inhibition of Stat2 expression Human respiratory syncytial virus 420
169 NS2 A non-stractural protein that mediates inhibition of Stat2 expression Human respiratory syncytial virus 375
170 OspA outer membrane lipoprotein; major lipoprotein antigen Piscirickettsia salmonis 489
171 PA (protective antigen) mediates entry of LF and EF into host cells Bacillus anthracis 2211
172 Parathyroid hormone (PTH) Endosecretory hormone Homo sapiens 0
173 PC-TP Promotes intermembrane transfer of phosphatidylcholines Homo sapiens 645
174 PfEMP1 Erythrocyte membrane constitutional protein 1 Plasmodium falciparum 1111
175 PGK1 Helps catalyze phosphate transfer for conversion of ADP to ATP. Saccharomyces cerevisiae 1251
176 pol human Immunodeficiency Virus (HIV-1) 0
177 pol pol polyprotein human Immunodeficiency Virus (HIV-1) 3000
178 pol pol protein. Simian immunodeficiency virus 3183
179 porcine alpha-lactalbumin Promotes synthesis of lactose Sus scrofa 426
180 PPAT Catalyzes CoA biosynthesis Pyrococcus abyssi 471
181 pro-urokinase (puk) activates fibrin-bound plasminogen Homo sapiens 1236
182 ProDer p 1/DNA ProDer p 1 major mite allergen precursor Dermatophagoides pteronyssinus 909
183 PTH Regulates calcium phosphorus metabolism. Homo sapiens 348
184 Ptilosarcus gurneyi GFP reporter gene Ptilosarcus gurneyi 714
185 Renilla luciferase reporter gene Renilla reniformis 945
186 Renilla mulleri GFP reporter gene Renilla mulleri 702
187 rev human immunodeficiency virus (HIV1) 2639
188 RH1 Useful chiral synthon for the chemical syntheses of pharmaceuticals. Dactylosporangium sp. 819
189 rtTA transcription factor Not specified 747
190 S protein surface spike glycoprotein SARS coronavirus 3768
191 S2 unknown, may interact with Gag EIAV 198
192 SAP Ribosome inactivation Saponaria officinalis 762
193 sbwAFP Choristoneura fumiferana 0
194 sbwAFP Choristoneura fumiferana 0
195 sbwAFP Choristoneura fumiferana 0
196 Sgp (SIV gag-pol) structural genes SIVmnd-2 4346
197 SIVmac239 Gag capsid protein SIV 1533
198 smGCPR histamine receptive G-protein coupled receptor Schistosoma mansoni 1683
199 Somatotropin Growth hormone Homo sapiens 582
200 Somatotropin (PST) Hormone precusor Sus scrofa 576
201 SoPCG Small blue copper protein which transfers electrons from the cytochrome bdf complex to photosystem 1. Spinacia oleracea 507
202 soxE Sulfocyanin (SynEII, a blue copper protein) Sulfolobus acidocaldarius 600
203 Spike Spike glycoprotein. SARS coronavirus Tor2 3768
204 Ssh10 DNA binding protein Sulfolobus shibatae 0
205 TAR1 Enzyme: NADPH-cytochrome P450 reductase Triticum aestivum 2022
206 tat transactivator protein human immunodeficiency virus (HIV1) 306
207 tat transactivator protein human immunodeficiency virus (HIV1) 261
208 Tat-1wt Important in viral infectivity and pathogenesis human Immunodeficiency Virus (HIV-1) 219
209 Tat-2wt Important in viral infectivity and pathogenesis human Immunodeficiency Virus (HIV-2) 426
210 TCE Hydrolyzes carboxylesters Tribolium castaneum 1554
211 TEL Provides elastic properties to tissues Homo sapiens 2274
212 tetR The production of the rtTA (reverse tet transactivator) transcription factor is induced by doxycyclin. The active protein can induce expression from promoters containing tetO. E. coli 618
213 tha Sweetner in human food and feed additive. Thaumatococcus daniellii 621
214 Thy-1 Mus musculus 489
215 Tlc Transports ATP into the R. prowazekii cell from the cytoplasm of the host cell. Rickettsia prowazekii 1497
216 TNNT2 Plays an important role in the regulation of muscle contraction in response to alterations in calcium concentration. Homo sapiens 888
217 TP2 Replace somatic and testis specific histones in the spermatid chromatin during spermiogenesis Rattus norvegicus 345
218 transglutaminase (TGase) An enzyme that catalyzes acyl transfer reactions between the gamma-carboxy-amide group of a glutamine residue in a peptide chain and the primary amine. Streptomyces mobaraensis 1224
219 U51 7-tm receptor homologous to cellular opioid receptors Human herpesvirus 6 906
220 UL26 protease, capsid assembly protein Herpes simplex virus 1 774
221 vif Promote viral infectivity human immunodeficiency virus (HIV1) 579
222 VP1 Capsid protein of FMDV Foot-and-mouth disease virus (FMDV) 639
223 VP1 Capsid protein complex Foot-and-mouth disease virus - type O 6969
224 VP6 of protein capsid which encases human rotavirus group A Homo sapiens 1194
225 VP6 Sole structural component of middle layer of rotavirus capsid Rotavirus A 1194
226 vpu Enhance viral particle release human immunodeficiency virus (HIV1) 246
227 VSV-G G protein Vesicular Stomatitis Virus 1536
228 wt p24gag human immunodeficiency virus (HIV1) 694
229 WTA (luxA) luciferase Photorhaddus luminsecens 1083
230 WTB (luxB) luciferase Photorhaddus luminsecens 984
231 wtgag DNA binding ( GO:0003677 ), RNA binding ( GO: 0003723), RNA-directed DNA polymerase activity ( GO: 0003964) human immunodeficiency virus (HIV1) 1539
232 wtgag DNA binding ( GO:0003677 ), RNA binding ( GO: 0003723), RNA-directed DNA polymerase activity ( GO: 0003964) human immunodeficiency virus (HIV1) 1539
233 wtgag DNA binding ( GO:0003677 ), RNA binding ( GO: 0003723), RNA-directed DNA polymerase activity ( GO: 0003964) human Immunodeficiency Virus Type 1 1539
234 wtgag DNA binding ( GO:0003677 ), RNA binding ( GO: 0003723), RNA-directed DNA polymerase activity ( GO: 0003964) Human immunodeficiency virus 1 (HIV-1) 1539
235 wtgag DNA binding ( GO:0003677 ), RNA binding ( GO: 0003723), RNA-directed DNA polymerase activity ( GO: 0003964) Human immunodeficiency virus 1 (HIV-1) 1539
236 wtgag Pr55gag polyprotein comprises the viral capsid, nucleic capsid, and matrix protein. HIV-1 1539
237 wtGFP Reporter gene Aequorea victoria 717
238 wtGluClα1 chloride channel Caenorhabditis elegans 1386
239 wtGluClβ chloride channel Caenorhabditis elegans 1305
240 wtNS3/4A CTL epitope Hepatitis C virus 2571
241 wtROS negative regulator for virC and virD operons Agrobacterium tumefaciens 429
242 xynB Hydrolyzes xylan Dictyoglomus thermophilum 1083
243 Yellow fluorescent protein (YFP) Reporter gene (T203Y from GFP) Aequorea victoria 717
 
 

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